Ai4 2025, one of the largest artificial intelligence conferences in North America, will take place in Las Vegas from 11 to 13 August. The event is expected to attract over 8,000 participants from 85 countries, including business decision-makers, technologists, researchers and public sector representatives, said a statement.
Held at the MGM Grand, the conference focuses on how artificial intelligence is being implemented across 21 industry tracks. These include healthcare, finance, cybersecurity, retail, manufacturing and education. The agenda features more than 600 confirmed speakers, over 250 exhibiting companies and content designed to address both technical and regulatory challenges.
“This year, we’ve elevated the conference to reflect the rapid evolution of generative AI, but also the practical challenges of integration, the urgency of ethical design, and the growing demand for cross-industry collaboration,” said Michael Weiss, Co-Founder, Ai4.
Attendees will encounter a mix of practical sessions, research insights and enterprise case studies focused on generative AI, AI regulation, risk frameworks and agent-based systems. Industry-specific tracks aim to help professionals understand how AI tools are being integrated into sector workflows, product pipelines and infrastructure.
The keynote programme spans three days. Randi Weingarten, President of the American Federation of Teachers, will open the first set of talks with a session on how AI technologies intersect with education policy and classroom learning. Stanford professor and MongoDB’s Chief AI Scientist Tengyu Ma will discuss the current landscape of retrieval-augmented generation (RAG) systems.
The second day features Geoffrey Hinton, often referred to as the “godfather of AI,” in conversation with Bloomberg News reporter Shirin Ghaffary, offering insights from decades of research into neural networks.
Sessions on the same day include a joint keynote by actor Breckin Meyer and Arcana Labs’ Chief Operating Officer Guy Ronen, focusing on AI in entertainment. Emmett Shear, the former interim CEO of OpenAI, is also scheduled to speak on alignment challenges in current AI systems, while Catalina Herrera from Dataiku will address concerns about enterprise AI maturity.
The final day of keynotes includes Stanford’s Fei-Fei Li, who will discuss human-centred AI in conversation with CNN’s Matt Egan. Cisco’s President and Chief Product Officer Jeetu Patel will also participate in a keynote on the rise of agentic systems in enterprise settings, followed by Colossal Biosciences’ Ben Lamm speaking about AI’s application in de-extinction projects.
Beyond keynotes, Ai4 2025 includes deep-dive sessions through its Research Summit, where academics and engineers will present on the transition from lab environments to production AI. Pre-conference workshops, led by General Assembly, provide optional training on applied machine learning and generative chaining methods.
The exhibition floor will showcase live demonstrations of AI applications from more than 250 companies. Product teams will highlight capabilities in AI governance, infrastructure, automation and generative design systems, with an emphasis on business-ready solutions.
Ai4 has been held annually since 2018. It has gained relevance as a neutral platform to discuss enterprise adoption, public governance and sector-specific risks related to artificial intelligence. The 2025 event comes at a time of increased corporate interest in generative tools and evolving regulatory frameworks across the European Union, United States and Asia.
A 2024 report from PwC found that more than 70% of companies in the US now deploy artificial intelligence in at least one function, with the fastest uptake in marketing, IT, customer support and logistics. Industry analysts say many enterprises are still navigating issues related to data privacy, explainability, and skills shortages in AI integration.
Ai4 2025 aims to reflect these realities with sessions that combine technical depth, policy relevance and cross-industry dialogue on what AI deployment looks like today and what is changing.

